2-(4-Chloro-2,5-diMethoxyphenyl)-N-(2-Methoxybenzyl)ethanaMine hydrochloride

2C-C is a 2,5-dimethoxyphenethylamine with a chlorine atom at the four position of the aromatic ring. A known hallucinogen, this compound stimulates monoamine receptor activity and inhibits the re-uptake of serotonin and norepinephrine in rat brain synaptosomes (IC50s = 31 and 63 μM, respectively). 25C-NBOMe is a derivative of 2C-C having an N-(2-methoxybenzyl) addition at the amine. This addition increases the affinity and selectivity for the 5-HT2A receptor over other serotonin receptors. Radiolabeled 25C-NBOMe has been used for positron emission tomography imaging of the 5-HT2A receptor in porcine brain. This product is intended for forensic and research uses.