LONGR3IGF-I is a recombinant analog of human insulin-like growth factor-I (IGF-I) that has been specifically engineered for the enhancement of cell culture performance. It is more biologically potentin vitrothan either insulin or native IGF-I and has been shown to significantly increase recombinant protein production. It is ideal for both research and large-scale culture systems utilizing serum-free or low-level serum applications. LONG R3IGF-I has been used with numerous cell types including CHO, vaccine-producing cell lines, fibroblasts and stem cells. All cell types that have a growth response to insulin in cell culture have the potential to respond to LONG R3IGF-I. LONG R3IGF-I provides equivalent or better performance to recombinant insulin depending on the cell line and clone.LONG R3IGF-I is produced in anEscherichia coliexpression system without the use of animal-derived components.
