Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 1 month.
Safety Information
Symbol(GHS)
Signal word
Danger
Hazard statements
H301:Toxic if swalloed
H413:May cause long lasting harmful effects to aquatic life
Precautionary statements
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
Description
HIF-2α-I2 (1422955-31-4) is a potent and selective HIF-2α inhibitor, Kd=81 nM.1?Binds to the HIF-2α PAS-B domain2?and interferes with Hif-2α / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2α displaying a >60-fold selectivity over HIF-1α.1,2