Adenosine 2′-monophosphate (2′-AMP) is a derivative of AMP with the phosphate bound at the 2'-position as opposed to the 5'-position in AMP. It can be used as a tool for studying adenosine-based cell regulation. 2′-AMP has been used in the synthesis of a novel photoaffinity label for the coenzyme site of porcine NADP-specific isocitrate dehydrogenase.