Varenicline suppliers

Varenicline

CAS:: 249296-44-4

MF:: C13H13N3

MW:: 211.26

Use：: Varenicline, a partial agonist of the a4b2 nicotinic receptor, is a first-in-class drug launched by Pfizer as an aid to smoking cessation treatment. Varenicline exhibits dual action by decreasing craving and withdrawal symptoms, and by decreasing the reinforcement associated with smoking. The addictive properties of nicotine are thought to be mediated in part through its action as an agonist at α4β2 neuronal nicotinic acetylcholine receptors (nAChRs). Activation of α4β2 receptors by nicotine increases the release of dopamine in the mesolimbic system, an effect that is shared by most drugs of abuse. As nicotine levels decrease, dopamine levels decline, which in turn stimulates the urge to smoke. Additionally, a reduced dopaminergic tone due to abstinence from smoking stimulates craving and the withdrawal syndrome. A partial agonist of α4β2 receptors such as varenicline is expected to elicit a moderate and sustained increase in dopamine levels to relieve craving and withdrawal symptoms. In addition, by competitively binding to a4b2 receptors and inhibiting nicotineinduced dopaminergic activation, a partial agonist could attenuate the pharmacologic reward associated with smoking.

More▼

You can find Varenicline suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Capot Chemical Co.,Ltd.

Varenicline
Remarks: Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
TEL: 571-85586718
CHINA Trader

Henan Tianfu Chemical Co.,Ltd.

Varenicline
Remarks: Purity: 99% | Package: 25KG;5KG;1KG
TEL: 0371-+86-0371-55170693
CHINA Trader

career henan chemical co

Raloxifene
Remarks: Purity: 99% | Package: 3ASSAYS;3USD
TEL: 0371-86658258
CHINA Reagent

￥3.00/3ASSAYS

BOC Sciences

Varenicline
Remarks: Purity: > 98% | Package: 1g | CustNote: BOC Sciences also provides custom synthesis services for Varenicline.
UNITED STATES Trader

CONIER CHEM AND PHARMA LIMITED

varenicline
Remarks: Purity: 0.99 | Package: 1kg
CHINA Trader

AFINE CHEMICALS LIMITED

VARENICLINE
Remarks: Purity: 99% | Package: USP EP CP
TEL: 0571-85134551
CHINA Trader

XI'AN TIANGUANGYUAN BIOTECH CO., LTD.

Varenicline
Remarks: Purity: 99% | Package: 100G; 1KG; 5KG; 25KG | CustNote: Pharmaceutical grade
TEL: +86-029-86333380
CHINA Trader

Dayang Chem (Hangzhou) Co.,Ltd.

Varenicline
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Wholesale price
TEL: 571-88938639
CHINA Trader

Zhejiang J&C Biological Technology Co.,Limited

Varenicline
Remarks: Purity: 99% | Package: 5KG;1KG
TEL: 1-2135480471
CHINA Trader

LEAP CHEM CO., LTD.

Varenicline
Remarks: Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
TEL: 852-30606658
CHINA Trader