Norepinephrine suppliers

Norepinephrine

CAS:: 51-41-2

MF:: C8H11NO3

MW:: 169.18

SecurityInformation

Symbol(GHS) ：: GHS06

Signal word ：: Danger

Hazard statements ：: H300+H310+H330

Precautionary statements ：: P260-P262-P264-P280-P302+P352+P310-P304+P340+P310

Hazard Codes ：: T+,C,F

Risk Statements ：: 26/27/28-34-11-28

Safety Statements ：: 28-36/37-45-36/37/39-26-16-20

RIDADR ：: UN 2811 6.1/PG 2

WGK Germany ：: 3

RTECS ：: DN5950000

F ：: 8-10-23

HazardClass ：: 6.1

PackingGroup ：: II

HS Code ：: 29225090

Toxicity：: dni-hmn:oth 5800 nmol/L CNREA8 40,1414,80

Use：: Norepinephrine (NE, Levophed) differs from DA onlyby addition of a 1-OH substituent (β-OH-DA) and from Eonly by lacking the N-methyl group. Like DA, it is polar andrapidly metabolized by both COMT and MAO, resulting inpoor oral bioavailability and short DOA (1 or 2 minutes evenwhen given intravenously). It is a stimulant of α1-, α2-, andβ1-adrenoceptors (notice that lacking the N-methyl group resultsin lacking β2- and β3-activity). It is used to counteractvarious hypotensive crises, because its α-activity raisesblood pressure and as an adjunct treatment in cardiac arrestbecause its β-activity stimulates the heart. It has limitedclinical application caused by the nonselective nature of itsactivities.

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Hebei Mojin Biotechnology Co., Ltd