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ChemicalBook >> CAS DataBase List >>Imipramine hydrochloride

Imipramine hydrochloride suppliers

Imipramine hydrochloride

CAS:: 113-52-0

MF:: C19H25ClN2

MW:: 316.87

SecurityInformation

Symbol(GHS) ：: GHS06

Signal word ：: Danger

Hazard statements ：: H300

Precautionary statements ：: P264-P270-P301+P310-P405-P501

Hazard Codes ：: Xn,T,F

Risk Statements ：: 23/25-36/38-36/37/38-22-39/23/24/25-23/24/25-11

Safety Statements ：: 7-16-24-33-45-36-26-36/37

RIDADR ：: UN 1230 3/PG 2

WGK Germany ：: 3

RTECS ：: HO1925000

TSCA ：: Yes

HS Code ：: 2933995800

Toxicity：: LD50 in mice, rats (mg/kg): 400, 490 orally; 110, 90 i.p. (Tobe)

Use：: Imipramine hydrochloride, 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine monohydrochloride(Tofranil), is the lead compound of the TCAs. It is also a closerelative of the antipsychotic phenothiazines (replace the10–11 bridge with sulfur, and the compound is the antipsychoticagent promazine). It has weaker D2 postsynaptic blockingactivity than promazine and mainly affects amines (5-HT,NE, and DA) via the transporters. As is typical of dimethylaminocompounds, anticholinergic and sedative (central H1block) effects tend to be marked. The compound per se has a tendency toward a high 5-HT-to-NE uptake block ratio andprobably can be called a serotonin transport inhibitor(SERTI). Metabolic inactivation proceeds mainly by oxidativehydroxylation in the 2-position, followed by conjugationwith glucuronic acid of the conjugate. Urinary excretion predominates(about 75%), but some biliary excretion (up to25%) can occur, probably because of the large nonpolargrouping. Oxidative hydroxylation is not as rapid or completeas that of the more nucleophilic ring phenothiazine antipsychotics;consequently, appreciable N-demethylation occurs,with a buildup of norimipramine (or desimipramine).

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You can find Imipramine hydrochloride suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Henan Tianfu Chemical Co.,Ltd.

Imipramine hydrochloride
Remarks: Purity: 99% | Package: 25KG;5KG;1KG
TEL: 0371-+86-0371-55170693
CHINA Trader

career henan chemical co

Imipramine hydrochloride
Remarks: Purity: 98% | Package: 1KG;1USD
TEL: 0371-86658258
CHINA Reagent

￥1.00/1KG

CONIER CHEM AND PHARMA LIMITED

imipramine hydrochloride
Remarks: Purity: 0.99 | Package: 1kg
CHINA Trader

TargetMol Chemicals Inc.

Imipramine hydrochloride
Remarks: Purity: 99.78% | Package: 100mg;53USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

Hefei TNJ Chemical Industry Co.,Ltd.

Imipramine HCl
TEL: 0551-65418671
CHINA Reagent

AFINE CHEMICALS LIMITED

IMIPRAMINE HYDROCHLORIDE
Remarks: Purity: 99% | Package: USP EP CP
TEL: 0571-85134551
CHINA Trader

Dayang Chem (Hangzhou) Co.,Ltd.

Imipramine hydrochloride
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot sales
TEL: 571-88938639
CHINA Trader

TargetMol Chemicals Inc.

Imipramine hydrochloride；G 22355;Tofranil;Imipramine (hydrochloride);Melipramine;Imipramine HCl
Remarks: Package: 1 mL * 10mM (in DMSO)；100 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Reagent

PT CHEM GROUP LIMITED

Imipramine hydrochloride
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot sales
TEL: 0371-+86-85511178
CHINA Trader

GIHI CHEMICALS CO.,LIMITED

Imipramine hydrochloride
Remarks: Purity: 99 | Package: 5KG;1KG,25kg
TEL: 0571-86217390
CHINA Trader