Galantamine Hydrobromide suppliers

Galantamine Hydrobromide

CAS:: 1953-04-4

MF:: C17H22BrNO3

MW:: 368.27

SecurityInformation

Symbol(GHS) ：: GHS06

Signal word ：: Danger

Hazard statements ：: H301

Precautionary statements ：: P264-P270-P301+P310-P405-P501

Hazard Codes ：: T

Risk Statements ：: 25

Safety Statements ：: 45-36/37/39-22

RIDADR ：: UN 2811 6.1/PG 3

WGK Germany ：: 3

RTECS ：: DF8075000

HazardClass ：: 6.1

PackingGroup ：: II

HS Code ：: 29399990

Toxicity：: LD50 i.v. in mice (mg/kg): 5.2 ± 0.2 (Friess)

Use：: Galantamine hydrobromide is a kind of tertiary amino alkaloid and is a reversible competitive inhibitor of cholinesterase. With the deepened understanding of the Alzheimer’s disease (AD) pathogenesis, people have started the study of using this product for treating AD in the early 1980s. In 1987, the United States scholars Bonnie had first successfully receive a patent of applying galantamine hydrobromide for treatment of AD. After this, many countries, one after another, have carried out related pharmacological, pharmacodynamic and pharmacokinetic studies related to it. This result had showed that galantamine hydrobromide, as the second-generation cholinesterase inhibitors, targeted on nerve synapses by competing with acetylcholine for binding to the cholinesterase and further blocking this enzymatic degradation of acetylcholine and therefore increasing the acetyl choline concentration inside the brain.

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You can find Galantamine Hydrobromide suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Shaanxi LonierHerb Bio Technology Co Ltd