FALECALCITRIOL suppliers

FALECALCITRIOL

CAS:: 83805-11-2

MF:: C27H38F6O3

MW:: 524.58

Use：: Falecalcitriol, previously known as flocalcitrol, was launched by several codevelopers in Japan for the treatment of secondary hyperthyroidism (SHPT). This hexafluorinated analog of 1α,25-dihydroxyvitamin D3 (calcitriol), the hormonally active form of vitamin D3, can be obtained by several different synthetic routes from a conveniently protected cholestenol, a key step being an aldol reaction with hexafluoroacetone. Falecalcitriol is several times more active than 1,25(OH)2D3 in regulating the proliferation of parathyroid cells and parathyroid hormone (PTH) synthesis that are believed to be mediated through binding to VDR, a nuclear receptor for vitamin D; furthermore, it was proposed that a bioactive 23S-hydroxylated metabolite, resistant to further metabolism, contributes to the retention of an active compound for longer in cells and so, to significantly lengthen the duration of action. In a comparative clinical study conducted in hemodialysis patients with moderate to severe SHPT, falecalcitriol was found to be more active than alfacalcidol in suppressing parathyroid hormone without triggering hypercalcemia.

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You can find FALECALCITRIOL suppliers, manufacturers, and distributors from countries such as China, United States and the Canada here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

ChemExpress

FALECALCITRIOL
Remarks: Purity: 99% | Package: 100g;1kg;10kg
TEL: +86-021-58950125
CHINA Service provider

Capot Chemical Co.,Ltd.

Falecalcitriol
Remarks: Purity: NLT 98% | Package: 1G;1KG;100KG
TEL: 571-85586718
CHINA Trader

CONIER CHEM AND PHARMA LIMITED

falecalcitriol
Remarks: Purity: 0.99 | Package: 1kg
CHINA Trader

career henan chemical co

FALECALCITRIOL
Remarks: Purity: 99% | Package: 1KG;7USD
TEL: 0371-86658258
CHINA Trader

￥7.00/1KG

TargetMol Chemicals Inc.

Falecalcitriol
Remarks: Purity: 98.00% | Package: 1 mg；10 mg；5 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

Dayang Chem (Hangzhou) Co.,Ltd.

Falecalcitriol
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot sales
TEL: 571-88938639
CHINA Trader

CR Corporation Limited

FALECALCITRIOL
CHINA Trader

Hefei TNJ Chemical Industry Co.,Ltd.

Falecalcitriol
TEL: 0551-65418684
CHINA Manufacturer

TargetMol Chemicals Inc.

Falecalcitriol
Remarks: Package: 50mg;3980USD|100mg;5500USD
TEL: +1-781-999-5354
UNITED STATES Reagent

PT CHEM GROUP LIMITED

Falecalcitriol
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot sales
TEL: 0371-+86-85511178
CHINA Trader