Amoxapine suppliers

Amoxapine

CAS:: 14028-44-5

MF:: C17H16ClN3O

MW:: 313.78

SecurityInformation

Symbol(GHS) ：: GHS07

Signal word ：: Warning

Hazard statements ：: H302

Precautionary statements ：: P264-P270-P301+P312-P501

Hazard Codes ：: Xn

Risk Statements ：: 22

Safety Statements ：: 36

RIDADR ：: 3249

WGK Germany ：: 3

RTECS ：: HQ4025500

HazardClass ：: 6.1(b)

PackingGroup ：: III

HS Code ：: 2934990002

Toxicity：: LD50 in mice (mg/kg): 122 i.p.; 112 orally (Howell, 1972)

Use：: Consideration of the structure of amoxapine, 2-chloro-11-(1-piperazinyl)dibenz-[b,f] [1,4]oxazepine (Asendin), reinforcesthe fact that many antidepressants are very closelyrelated to antipsychotics. Indeed, some, including amoxapine,have significant effects at D2 receptors. The Nmethyl–substituted relative of amoxapine is the antipsychoticloxapine (Loxitane). The 8-hydroxy metabolite ofamoxapine is reportedly active as an antidepressant and asa D2 receptor blocker.

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