Topotecan suppliers

Topotecan

CAS:: 123948-87-8

MF:: C23H23N3O5

MW:: 421.45

Use：: Topotecan was launched in the US for the second-line treatment of ovarian cancer. It can be prepared in four steps from camptothecin and is a water soluble derivative of the natural product with decreased toxicity. Unlike its chemical relative irinotecan, topotecacan in not a prodrug and does not require bioactivation. It is an inhibitor of topoisomerase I. Specifically, it inhibits the release of topoisomerase I from DNA, where it relaxes supercoiled DNA, giving rise to single-strand breaks. When the replication fork reaches this complex, double-stand breaks can occur. This signals apoptosis and eventually gives rise to cell death. Evidence indicates hycamtin is safe for people with impaired hepatic function.

More▼

You can find Topotecan suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Pushan Industry (Shaanxi) Co., Ltd.

Topotecan
Remarks: Purity: 99% | Package: 25KG
TEL: 029-81310890
CHINA Service provider

Henan Tianfu Chemical Co.,Ltd.

TIANFU-CHEM 123948-87-8 Topotecan
Remarks: Purity: 99% | Package: 25KG;5KG;1KG
TEL: 0371-+86-0371-55170693
CHINA Trader

ATK CHEMICAL COMPANY LIMITED

3-amino-2,2-dimethyl-propionitrile; hydrochloride
Remarks: Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G
TEL: 21-51877795
CHINA Reagent

career henan chemical co

Topotecan
Remarks: Purity: 98% | Package: 1KG;1USD
TEL: 0371-86658258
CHINA Reagent

￥1.00/1KG

Chengdu Biopurify Phytochemicals Ltd.

Topotecan
Remarks: Purity: >95%,98%,99% | Package: From mgs to grams,up to Kgs | CustNote: Can be customized in bulk scale
TEL: +86-28-82633860
CHINA Reagent

CONIER CHEM AND PHARMA LIMITED

topotecan
Remarks: Purity: 0.99 | Package: 1kg
CHINA Trader

TargetMol Chemicals Inc.

Topotecan
Remarks: Purity: 95.19% | Package: 5mg;32USD|10mg;45USD|25mg;76USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

Win-Win chemical CO., Limited

(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizine-8-carboxylic acid;hydrochloride
Remarks: Package: 1g,5g,10g
TEL: 0577-64498589
CHINA Trader

Shanghai UCHEM Inc.

Topotecan
Remarks: Purity: 0.99 | Package: 25kg;1kg
CHINA Trader

Dideu Industries Group Limited

Topotecan
Remarks: Purity: 99.9%|Package: 1g;1.1USD
TEL: +86-29-89586680
CHINA Trader

￥1.10/1g