Autocamtide-2 Related Inhibitory Peptide II - Calbiochem

Autocamtide-2 Related Inhibitory Peptide II - Calbiochem 화학적 특성, 용도, 생산

• 일반 설명

  An autocamtide-2 related inhibitory peptide (AIP) analog in which Ala³ and Val¹⁰ have been replaced with Lys and Phe, respectively. Acts as a highly specific, potent inhibitor of calmodulin-dependent protein kinase II (CaMKII) (IC₅₀ = 4.1 nM). Displays ~10-fold greater potency than AIP (Cat. No. 189480). Inhibits PKC at higher concentrations (IC₅₀ = 1 μM), but does not affect the activities of CaMKIV or PKA (IC₅₀ >100 μM).

• Biochem/physiol Actions

  Primary TargetCAM Kinase-2

Autocamtide-2 Related Inhibitory Peptide II - Calbiochem 공급 업체

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