SD 2590 HYDROCHLORIDE

SD 2590 HYDROCHLORIDE 화학적 특성, 용도, 생산

• 개요

  SD 2590 is an inhibitor of matrix metalloproteinase-2 (MMP-2), -3, -8, -9, and -13 (IC₅₀s = <0.1, 28.7, 1.7, 0.18, and <0.1 nM, respectively). It is selective for these MMPs over MMP-1 and MMP-7 (IC₅₀s = >10,000 and 7,000 nM, respectively). SD 2590 (10 mg/kg per day) inhibits dilation of the left ventricle in rats following myocardial infarction (MI) compared to MI vehicle control animals.

• 용도

  SD 2590 Hydrochloride is an orally active MMP inhibitor with efficacy in cancer, arthritis and cardiovascular disease.

SD 2590 HYDROCHLORIDE 공급 업체

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