THPN

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H302：삼키면 유해함

THPN 화학적 특성, 용도, 생산

• 용도

  THPN is a Nur77 agonist. THPN binds Nur77 and promotes translocation of the receptor to the mitochondria resulting in autophagy in melanoma cell lines.

• 일반 설명

  THPN or 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, is a derivative of cytosporone B.

• Biochem/physiol Actions

  THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma. Co-application of THPN with Akt2 inhibitors significantly represses tumor growth in xenograft mouse model.

THPN 공급 업체

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