SENKIRKIN

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Danger

• 유해·위험 문구

  H301：삼키면 유독함

• 예방조치문구

  P301+P310：삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.

SENKIRKIN 화학적 특성, 용도, 생산

• 개요

  A further hepatotoxiC alkaloid present in Senecio kirkii Hook, S. renardi and Nardosrnia laevigata. The base has [α]²⁵_D - 16° (c 1.89, MeOH) or[α]¹⁵_D - 6.2° (c 1.91, CHCI₃). It forms colourless plates when crystallized from either Me₂CO or AcOEt and yields a picrate, m.p. 225.5-226°C and a picrolonate, m.p. 109- 110°C. The ultraviolet spectrum shows a single absorption maximum at 219 mp.. Several crystalline salts and derivatives are known, e.g. the aurichloride, m.p. 182.5-183.5°C; platinichloride, m.p. 196-7°C (dec.); bitartrate, m.p. 201°C; reineckate, m.p. 169-171°C; picrate, m.p. 225- 225.5°C; picrolonate, m.p. 138°C and the methiodide, m.p. 194-6°C (dec.). The O-acetate occurs naturally (q.v.) in Senecio kirkii.

• Safety Profile

  Poison by ingestion and intraperitoneal routes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Nox

• 참고 문헌

  Briggs, Mangan, Russell., J. Chern. Soc., 1891 (1948)
  Massagetov, Kuzovkov.,J. Gen. Chern., USSR, 23, 158 (1953)
  Danilova, Konovalova., ibid, 30, 1921 (1961)
  Danilova, Koretskaya, Utkin., ibid, 31, 3815 (1961)
  Wunderlich., Chern. Ind., 2089 (1962)
  Briggs et al., J. Chern. Soc., 2492 (1965)

SENKIRKIN 공급 업체

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