Ethyl diazoacetate

한글명:Ethyl diazoacetate

카스 번호623-73-4

상품명:Ethyl diazoacetate

CBNumberCB9241343

분자식C4H6N2O2

포뮬러 무게114.1

MOL 파일623-73-4.mol

화학적 성질

녹는점	-22 °C (lit.)
끓는 점	140-141 °C/720 mmHg (lit.)
밀도	1.085 g/mL at 25 °C (lit.)
굴절률	n20/D 1.46(lit.)
인화점	115 °F
저장 조건	2-8°C
용해도	Chloroform (Slightly), DMSO (Soluble), Hexane (Slightly), Methanol (Slightly)
물리적 상태	기름
색상	연한 노란색에서 주황색까지
Merck	13,3021
BRN	107654
NIST	Ethyl diazoacetate(623-73-4)

위험 및 안전 성명

위험품 표기	Xn,F
위험 카페고리 넘버	5-10-22-40-67-65-48/20-38-11-63
안전지침서	36/37-62-16
유엔번호(UN No.)	UN 1993 3/PG 3
WGK 독일	3
RTECS 번호	AG5775000
위험 등급	3.2
포장분류	III
HS 번호	29270000

그림문자(GHS)

Ethyl diazoacetate 화학적 특성, 용도, 생산

화학적 성질
Liquid.
용도
Reagent for ruthenium-catalyzed asymmetric cyclopropanation of alkenes.1
위험도
Flammable liquid that explodes when heated.
Safety Profile
Poison by ingestion and intravenous routes. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Can explode. Explodes on contact with tris(dimethy1amino) antimony. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS.
Purification Methods
It is a very volatile yellow oil with a strong pungent odour. EXPLOSIVE [distillation even under reduced pressure is dangerous and may result in an explosion — TAKE ALL THE NECESSARY PRECAUTIONS IF DISTILLATION IS TO BE CARRIED OUT]. It explodes in contact with conc H2SO4-trace acid causes rapid decomposition. It is slightly soluble in H2O, but is miscible with EtOH, *C6H6, pet ether and Et2O. To purify, dissolve it in Et2O [using CH2Cl2 instead of Et2O, protects the ester from acid], wash it with 10% aqueous Na2CO3, dry (MgSO4), filter and repeat as many times as possible until the Et2O layer loses its yellow colour, then remove the solvent below 20o (vacuum). Note that prolonged heating may lead to rapid decomposition and low yields. It can also be purified by steam distillation under reduced pressure but with considerable loss in yield. Place the residual oil in a brown bottle, keep below 10o, and use as soon as possible without distilling. For preparing esters usually the ethereal solution is used directly without purification. [Womack & Nelson Org Synth Coll Vol III 392 1955, UV: Miller & White J Am Chem Soc 79 5974 1957, Fieser 1 367 1967, Beilstein 3 IV 1495.]

Ethyl diazoacetate 준비 용품 및 원자재

Ethyl diazoacetate 공급 업체

Ethyl diazoacetate 관련 검색

Send Inquriy