Anti-ADAP78, Anti-Calcipressin 1, Anti-Calcipressin-1, Anti-Down Syndrome Candidate Region 1, Anti-DSC1, Anti-MCIP1, Anti-Myocyte-enriched calcineurin-interacting protein 1, Anti-RCAN1, Anti-RCN1, Anti-Regulator of calcineurin 1

Anti-ADAP78, Anti-Calcipressin 1, Anti-Calcipressin-1, Anti-Down Syndrome Candidate Region 1, Anti-DSC1, Anti-MCIP1, Anti-Myocyte-enriched calcineurin-interacting protein 1, Anti-RCAN1, Anti-RCN1, Anti-Regulator of calcineurin 1 화학적 특성, 용도, 생산

• 용도

  Anti-DSCR1 (C-terminal) antibody is suitable for use in western blot (2-4 μg/mL using HEK-293T cells expressing human DSCR1) and in immunoblotting (approx. 26 kDa).

• 일반 설명

  DSCR1 (Down Syndrome Candidate Region 1 is encoded by a gene mapped to human chromosome 21q22.1. DSCR1 belongs to a family of conserved proteins named regulators of calcineurin (RCAN), that in humans include RCAN, encoded by the DSCR1L1-2 genes. DSCR1 is highly expressed in the central nervous system (CNS) during early embryonic development, in heart, and in skeletal muscle.

• Biochem/physiol Actions

  Down Syndrome Candidate Region 1 or DSCR1 is a candidate gene involved in the pathogenesis of Down′s Syndrome (DS). DSCR1 is usually expressed in cardiac, skeletal and brain tissues, whereas its overexpression in fetal brain tissues is associated with DS. DSCR1 inhibits calcineurin-mediated mRNA synthesis.

Anti-ADAP78, Anti-Calcipressin 1, Anti-Calcipressin-1, Anti-Down Syndrome Candidate Region 1, Anti-DSC1, Anti-MCIP1, Anti-Myocyte-enriched calcineurin-interacting protein 1, Anti-RCAN1, Anti-RCN1, Anti-Regulator of calcineurin 1 공급 업체

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