acetyl carbromal

acetyl carbromal 화학적 특성, 용도, 생산

• Originator

  Acetylcarbromal ,Pfaltz and Bauer

• Manufacturing Process

  It was mixed 120 parts of urea and 258 parts of bromodiethylacetylbromide (prepared from diethylacetic acid anhydride and bromine). After 12 hours the mixture was heated for 3 hours at 100°C. The product was mixed with an aqueous solution of sodium bicarbonate and then was filtered. The obtained bromodiethylacetylurea was crystallized from diluted ethanol; melting point 114-118°C. The mixture of 474 parts of bromodiethylacetylurea, 1000 parts of acetic anhydride and 75 parts ZnCl2 was heated at 60°C for 1 hour. The product was stirred with 3000 parts of ice-water and then 1-acetyl-3-(α- bromo-α-ethylbutyryl)urea was filtered; melting point 108-109°C.

• Therapeutic Function

  Sedative, Hypnotic

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