LAUROLITSINE

LAUROLITSINE 화학적 특성, 용도, 생산

• 개요

  This noraporphiae alkaloid has been obtained from Litsea japonica and Neolitsea sericea and swells at 11 5-8°C before melting. It is dextrorotatory with [o:lbl + 102.5° (EtOH) and yields a picrate as yellow needles, m.p. 212°C (dec.) and a picrolonate, m.p. 239°C (dec.). The N-methyl derivative is identical with boldine.

• 용도

  Laurolitsine is an alkaloid extracted from Polyalthia longifolia var. pendula.

• 정의

  ChEBI: An isoquinoline alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV 1 integrase.

• 참고 문헌

  Nakasato, Nomura., Chem. Pharm. Bull., (Tokyo), 7, 780 (1959)
  Kozuka., J. Ph arm. Soc., Japan, 82, 1567 (1962)
  See also:
  Johns, Lamberton., Austral. J. Chem., 20, 1277 (1967)

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