니포폴린

니포폴린 화학적 특성, 용도, 생산

• Originator

  Furobactil,Carrion,France,1974

• Manufacturing Process

  20 g of nitrofurantoin are placed in 100 cc of dimethylformamide and the solution is heated to 75°C to 80°C. This temperature is maintained and 100 cc of 40% formaldehyde are added, followed by 10 g of freshly distilled morpholine. The heating is continued for one hour, the mixture cooled and filtered and the precipitate obtained is washed with 95% alcohol. 20 g of the desired product are obtained as yellow crystals which melt at 206°C.

• Therapeutic Function

  Antibacterial

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