유실요소

유실요소 화학적 특성, 용도, 생산

• Originator

  Nostyn,Ames,US,1956

• Manufacturing Process

  54 g of carbromal (2-bromo-2-ethylbutyryl-urea) in 600 cc of isopropanol was stirred and refluxed for 3 hours with 27.8 g of anhydrous silver oxide. The reaction mixture was filtered and the silver residue was extracted with 100 cc of boiling isopropanol. The filtered and dried solids which separated weighed 22.5 g and melted at 189°C to 190.5°C. Concentration of the filtrate yielded an additional 3.3 g of product which melted at 160°C to 170°C. These two crops were separately obtained as white needles by crystallization from alcohol and exhibited slight solubility in water. The first crop gave 21.7 g of 2- ethyl-cis-crotonyl urea with a melting point of 191°C to 193°C, and the second crop gave 0.9 g with a melting point of 191°C to 193°C for a total yield of 42.4 g or 63% of the theoretical.

• Therapeutic Function

  Sedative

유실요소 준비 용품 및 원자재

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