(R)-(-)-3-QUINUCLIDINYL BENZILATE

한글명:(R)-(-)-3-QUINUCLIDINYL BENZILATE

카스 번호62869-69-6

상품명:(R)-(-)-3-QUINUCLIDINYL BENZILATE

CBNumberCB8496960

분자식C21H23NO3

포뮬러 무게337.41

MOL 파일62869-69-6.mol

화학적 성질

저장 조건

2-8°C

위험 및 안전 성명

위험품 표기	T
위험 카페고리 넘버	23/24/25
안전지침서	22-36/37/39-45
유엔번호(UN No.)	UN 2811 6.1/PG 2
WGK 독일	3
RTECS 번호	DD4638000

그림문자(GHS)

(R)-(-)-3-QUINUCLIDINYL BENZILATE 화학적 특성, 용도, 생산

화학적 성질
Quinuclidinol benzilate (QNB) aka BZ, is a white crystalline solid. Odorless to fruitlike.
용도
(R)-(-)-3-Quinuclidinyl benzilate is a pharmacological agent used as muscarinic M3 antagonist for the inhaled treatment of chronic obstructive pulmonary disease (COPD).
잠재적 노출
Suspected reprotoxic hazard, drug; incapacitating agent. QNB is a glycolate anticholinergic compound that affects the CNS and peripheral nervous sys- tem (PNS) and is related to the drugs atropine, scopol- amine, and hyoscyamine. QNB is nonirritating; symptoms are delayed for several hours. QNB can be used to contami- nate water, food, and agricultural products. A highly potent drug and CNS depressant, QNB is a delayed-action inca- pacitating agent, usually dispersed as an aerosol, but it can also be used to penetrate skin when mixed with a solvent (such as DMSO), and to contaminate food and water. QNB appears to be widely used in pharmacologic research. The key to protection from QNB is prevention from entering the body with good quality aerosol filter and impermeable gloves and clothing. QMB is stable in most solvents, with a half-life of 3 to 4 weeks in moist air; it can be dispersed even with heat-producing munitions.
운송 방법
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. Military driver shall be given full and complete information regarding shipment and conditions in case of emergency. AR 50-6 deals specifically with the shipment of chemical agents. Shipments of agent will be escorted in accordance with AR 740-32.
비 호환성
May form explosive mixture with air. Decomposes at about 170℃ in air under prolonged heat- ing. After 1 or 2 hours at 200℃, it is completely decom- posed. Rate of decomposition is both temperature- and purity dependent. No effect on steel or stainless steel after 3 months @ 71℃. Aluminum and anodized aluminum are mildly attacked after 3 months @ 71℃. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanga- nates, perchlorates, chlorine, bromine, fluorine, etc.); con- tact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Contact with metals may evolve flammable hydrogen gas
폐기물 처리
Dispose of the material per IAW waste disposal methods provided below. Conduct general area monitoring with an approved monitor to con- firm that the atmospheric concentrations do not exceed the airborne exposure limit. If 10 wt.% sodium hydroxide is not available then the following decontaminants may be used instead and are listed in order of preference: Decontaminating Solution No. 2 , sodium carbonate and Supertropical Bleach Slurry (STB). Keep this chemical out of a confined space, such as a sewer, because of the possibility of an explosion, unless the sewer is designed to prevent the build-up of explosive concentrations. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or con- taminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your local or federal environmental protection agency for specific recommendations. If employees are required to clean-up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable.

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