Neurokinin B

Neurokinin B 화학적 특성, 용도, 생산

• 정의

  ChEBI: Neurokinin B is a polypeptide. It is a mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family is similar in structure and action to substance P and neurokinin A. It has the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the urinary bladder and uterus.

• Biochem/physiol Actions

  Neurokinin B is a ten-residue peptide. It is an endogenous tachykinin agonist with preference for the NK-3 receptor. It is a potent bronchoconstrictor and may have a neuromodulatory role in the brain. Neurokinin B has a role in slow synaptic or non-synaptic communication.

• 참고 문헌

  [1] LAUFERR. Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1985, 82 21: 7444-7448. DOI:10.1073/pnas.82.21.7444.
  [2] RANCENAOMI E. Neurokinin B and the hypothalamic regulation of reproduction.[J]. Brain Research, 2010, 1364: 116-128. DOI:10.1016/j.brainres.2010.08.059.
  [3] MARIA ASMAT F. R M Ramzan. Exogenous Neurokinin B Administration May Have a Strong Effect on Negative Feedback Loop of Hypothalamic Pituitary Thyroid Axis[J]. International Journal of Peptide Research and Therapeutics, 2019, 26 1: 1259-1267. DOI:10.1007/s10989-019-09925-0.

Neurokinin B 공급 업체

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