SBE 13 hydrochloride

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H302：삼키면 유해함

• 예방조치문구

  P280：보호장갑/보호의/보안경/안면보호구를 착용하시오.

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

SBE 13 hydrochloride 화학적 특성, 용도, 생산

• 개요

  SBE 13 is a potent inhibitor of polo-like kinase 1 (Plk1) (IC₅₀ = 0.2 nM) that targets the inactive conformation of the enzyme . It exhibits no activity against aurora A kinase and less effectively inhibits Plk2 (IC₅₀ > 66 μM) and Plk3 (IC₅₀ = 875 nM). SBE 13 induces cell cycle arrest, reduces cell proliferation (EC₅₀ = 5-60 μM), and induces apoptosis in a broad range of human cancer cell lines.

• 용도

  SBE13 Hydrochloride is a selective inhibitor of PLK1.

SBE 13 hydrochloride 공급 업체

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