| 안전지침서 | 22-24/25 |
| WGK 독일 | 3 |
| 독성 | Aconitase is the enzyme that reversibly interconverts citric acid, cis-aconitic acid, and isocitric acid in the tricarboxylic acid cycle (TCA) (formerly known as the citric acid or Krebs cycle) by dehydration and hydration reactions. Aconitase is the target for fluoroacetate, a potent rodenticide, that condenses with oxaloacetate to yield an aconitase inhibitor (fluorocitric acid), with resultant accumulation of citric acid and thus blockage of the TCA cycle, leading to an inhibition of aerobic energy production. |