L-라이신,N-(1-옥소헥사데실)글리실-L-히스티딜-

한글명:L-라이신,N-(1-옥소헥사데실)글리실-L-히스티딜-

카스 번호147732-56-7

상품명:Palmitoyl Tripeptide-1

CBNumberCB81214020

분자식C30H54N6O5

포뮬러 무게578.79

MOL 파일147732-56-7.mol

동의어(한글)

L-라이신,N-(1-옥소헥사데실)글리실-L-히스티딜-

화학적 성질

끓는 점	913.0±65.0 °C(Predicted)
밀도	1.105
저장 조건	Store at -20°C
용해도	DMF: 30 mg/ml; DMSO: 10 mg/ml; Ethanol: 30 mg/ml
물리적 상태	고체
산도 계수 (pKa)	3.16±0.10(Predicted)
시퀀스	Pal-Gly-His-Lys
InChIKey	BYUQATUKPXLFLZ-UIOOFZCWSA-N
SMILES	C(O)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CNC(=O)CCCCCCCCCCCCCCC

그림문자(GHS)

L-라이신,N-(1-옥소헥사데실)글리실-L-히스티딜- 화학적 특성, 용도, 생산

개요
A peptide is two or more amino acids joined together and is the building block of protein. Peptides fall into three main categories: signal peptides, carrier peptides, and those that inhibit nerve signals. Signal peptides, like palmitoyl tripeptide-1, act as messengers to cells, which trigger collagen synthesis, which then increases skin firmness.Palmitoyl tripeptide-1 is a small three amino acid signal peptide with the amino sequence of glycine-histidine-lysine (GHK). GHK is attached to palmitic acid (a fatty acid) to increase its skin penetration and oil solubility.
용도
Palmitoyl Tripeptide-1, has shown to have effects on on collagen, fibronectin, hyaluronic acid synthesis in human dermal fibroblasts, and thus can be used in preparation of antiaging cosmetic creams.
주요 응용
Palmitoyl Tripeptide-1 (Pal-GHK, SpecPed? PT1P) is useful in anti-aging products and wrinkle treatment products such as gels, serums, lotions and creams. Acting as messengers of cutaneous restructuration and repair, this peptide works synergistically to restore and maintain the skin's youthful appearance.
Clinical Use
Applying palmitoyl tripeptide-1 directly to your skin tells the cells to make more collagen, stimulating new collagen production. It requires at least one month or more to begin to see visible changes from new collagen with maximum results visible after 3 to 4 months. Erin Gilbert, MD, FAAD, Ph.D., and board-certified dermatologist and neuroscientist, continues: "Peptides can be included in serums, moisturizers, and masks," Gilbert explains. "They are also included in some topical serums used after micro-needling or superficial laser procedures to increase the penetration of the peptide and help the skin recover from the procedure."
Safety
The CIR Expert Panel concluded that peptides, such as palmitoyl tripeptide-1, are safe in cosmetics and self-care products. Environmental Working Group (EWG) currently scores palmitoyl tripeptide-1 as “1” or “low hazard.”Overall, peptides, such as palmitoyl tripeptide-1, mimic what already exists in the human body and research on peptides’ impact on the skin shows limited to no skin irritation. In terms of toxicity caused by peptides, there is no published research to document any known toxicity.

L-라이신,N-(1-옥소헥사데실)글리실-L-히스티딜- 공급 업체

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