2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one

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• 그림문자(GHS)

  

• 신호 어

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2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one 화학적 특성, 용도, 생산

• 용도

  Vicine is a pyrimidine glycosides, a precursor of the aglycons divicine and isouramil which is main factors of favism. It is found in faba/fava bean. Also, it is derived from Ethyl Glyoxylate (E918550), which is used as a reagent in the synthesis of a new class of cinnamyl-triazole compounds which can be used as selective inhibitors of human aromatase (cytochrome P 450 19A1)

• Purification Methods

  Crystallise Vicine from water (1%) or aqueous 85% EtOH, and dry it at 135o. [Bendich & Clements Biochim Biophys Acta 12 462 1953, Beilstein 31 H 163, 2 5 III/IV 4285.]

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