Creatine amidinohydrolase is a clinically important enzyme used in the determination of creatinine in blood and urine.
일반 설명
Creatinase is a homodimer that catalyzes hydrolysis of creatine. It consists of two monomer subunit and two defined domains; N and C terminal domains. C terminal fold have both the α helices and anti-parallel β sheet within two structurally similar domains.In between these two domains, there is a sulfhydryl group that acts as active site and the activity is metal independent.
Biochem/physiol Actions
Creatinase is a homodimer with subunit molecular weights of approximately 45 kDa. It catalyzes the hydrolysis of creatine, in the presence of H2O, to form urea and sarcosine.
CREATINE AMIDINOHYDROLASE 공급 업체
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