psilocybin: A hallucinogen, similarin effect to psimescaline, found incertain species of mushroom. It is accompaniedby a related, more active,compound psilocin. Both are classifiedas class A drugs in the UK. Theycan be detected by the Marquis testor the Froehde test.
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Psilocybin is the phosphoric acid ester of psilocin and appearsto be converted to psilocin as the active species invivo. It occurs in a mushroom, Psilocybe mexicana. Bothdrugs are active orally, with a short duration of action. Synthetic α-methyl–substituted relatives have a muchlonger duration of action and enhanced oral potency.Thissuggests that psilocin is metabolized by MAOs.