cannabichromene

한글명:cannabichromene

카스 번호20675-51-8

상품명:cannabichromene

CBNumberCB61400957

분자식C21H30O2

포뮬러 무게314.46

MOL 파일20675-51-8.mol

화학적 성질

녹는점	145°C
끓는 점	394.13°C (rough estimate)
밀도	1.0536 (rough estimate)
굴절률	1.5404 (estimate)
인화점	9℃
저장 조건	-20°C
용해도	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
물리적 상태	기름
산도 계수 (pKa)	9.68±0.40(Predicted)
색상	크리스탈
InChI	InChI=1S/C21H30O2/c1-5-6-7-10-17-14-19(22)18-11-13-21(4,23-20(18)15-17)12-8-9-16(2)3/h9,11,13-15,22H,5-8,10,12H2,1-4H3
InChIKey	UVOLYTDXHDXWJU-UHFFFAOYSA-N
SMILES	C1(C)(CC/C=C(\C)/C)OC2=CC(CCCCC)=CC(O)=C2C=C1
LogP	8.560 (est)

위험 및 안전 성명

유엔번호(UN No.)

UN1230 - class 3 - PG 2 - Methanol, solution

WGK 독일

HS 번호

9999999999

독성

dni-hmn:lyms 100 mmol/L FEPRA7 36,1748,77

NFPA 704:

	3
0		0

그림문자(GHS)

cannabichromene 화학적 특성, 용도, 생산

개요
Cannabichromene (CBC) is one of the most abundant cannabinoids found in the cannabis plant, next to CBD, THC, and CBG. It is particularly abundant in freshly harvested dry-type Cannabis material, and it is the second most abundant cannabinoid in some strains of marijuana growing in the USA. Like CBD, CBG does a poor job of binding to the endocannabinoid system's CB1 and CB2 receptors and is a non-psychoactive compound. Instead, CBC has been observed to have unique interactions with TRPV1 and TRPA1 receptors (vanilloid 1 and ankyrin 1 receptors). It has modest antinociceptive and anti‐inflammatory effects and potentiates some effects of Δ9‐tetrahydrocannabinol in vivo[1–2].
Biological Functions
More recently, it has been shown that cannabichromene (CBC) exerts antimicrobial, anti-inflammatory, analgesic and antidepressant-like activity in rodents. Pharmacodynamic studies have shown that CBC, like other plant natural products, is an inhibitor of endocannabinoid cellular reuptake and a weak inhibitor of monoacylglycerol lipase (MAGL) but is also a potent activator of transient receptor potential (TRP) ankyrin 1-type (TRPA1) channels. CBC was also recently found to stimulate the descending pathway of antinociception in the ventrolateral periaqueductal grey, probably through activation of TRPA1, inhibition of endocannabinoid inactivation and subsequent elevation of local endocannabinoid levels, and possibly via potentiation of adenosine signalling[3].
일반 설명
Cannabichromene (CBC) is a non-psychoactive cannabinoid of Cannabis that reportedly exerts anti-inflammatory, antimicrobial and analgesic activity. This Certified Snap-N-Spike^? solution standard is suitable for cannabichromene testing methods by GC/MS, HPLC or LC-MS/MS for Cannabis potency testing or impurity profiling, pharmaceutical research, and forensic analysis. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.
부작용
Dry Mouth: Similar to other cannabinoids, CBC can cause dry mouth. Staying hydrated can help mitigate this effect.
Fatigue: Some users feel tired after taking it, especially in higher doses. It's advisable to start with a low dose and gradually increase it to find the optimal amount.
Digestive Issues: In rare cases, it might cause mild digestive issues such as nausea or diarrhoea. Headache: Some people might experience headaches, particularly when starting or taking higher doses.
Dizziness: Occasional dizziness can occur, especially when standing up too quickly after consuming CBC.
Safety Profile
Poison by intravenous and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. Whenheated to decomposition it emits acrid smoke and irritating fumes

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