부타닉신

부타닉신 화학적 특성, 용도, 생산

• Originator

  Butanixin,ZYF Pharm Chemical

• Manufacturing Process

  5 g 2-chloronicotinic acid and 9.4 g p-n-butyl aniline were heated for 1 hour at 160°C by vigorous stirring under a nitrogen atmosphere. Then the mixture was dissolved in 2 N sodium hydroxide and extracted with benzene. The water layer was acidified and a precipitate obtained was filtered off, washed with water and dried. 5 g 2-[(4-butylphenyl)amino]-3-pyridinecarboxylic acid yielded. MP: 171°-173°C (deg.).

• Therapeutic Function

  Analgesic, Antiinflammatory

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