ANTI-BRAIN DERIVED NEUROTROPHIC FACTOR

ANTI-BRAIN DERIVED NEUROTROPHIC FACTOR 화학적 특성, 용도, 생산

• 용도

  Anti-BDNF antibody produced in rabbit has been used in immunohistochemistry and western blotting.

• 일반 설명

  The antibody shows ~5% cross-reactivity with recombinant human β?NGF and recombinant rat β?NGF.

• Biochem/physiol Actions

  Brain derived neurotrophic factor (BDNF) is involved in hippocampal function and verbal episodic memory in humans. Hence, variation in the BDNF gene expression alters these neurological functions. BDNF also plays a vital role in vascular function and participates in angiogenesis via the specific receptor tropomyosin-related kinase B (TrkB). It is involved in the pathogenesis of Alzheimer′s disease. ProBDNF interacts with p75 neurotrophin receptor, leading to long-term depression in the hippocampus.

ANTI-BRAIN DERIVED NEUROTROPHIC FACTOR 공급 업체

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