Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate 화학적 특성, 용도, 생산

• 용도

  3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine can be used as organic intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

• Synthesis

  
  1.Add DMAP (0.16 mmol, 20 mg) to a stirred suspension of 2'-deoxyuridine (1 mmol, 228 mg) in acetic anhydride (7.5 mL).2.Observe the reaction mixture become homogenous for 6 hours.3.Remove the volatiles in vacuum.4.Purify the residue by flash chromatography on silica gel eluted with EA/cyclohexane (4:1 → 19:1, v/v) to obtain 3',5'-di-O-acetyl-2'-deoxyuridine.

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate 준비 용품 및 원자재

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate 공급 업체

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