3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE

3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE 화학적 특성, 용도, 생산

• 용도

  Methyl-3,4-dephostatin has been used as:
  
  • an inhibitor for methyltransferases
  • a kinase-related inhibitor for human transglutaminase
  • a cysteine binding compound for screening its effect on C-terminal domain (CTD) of human immunodeficiency virus (HIV-1) capsid protein
  
  

• Biochem/physiol Actions

  Methyl-3,4-dephostatin is a tyrphostin-related compound isolated from Streptomyces MJ742-NF5 strain. It favors nerve growth factor-based neurite formation in pheochromocytoma PC12 cells. Being a stable analog of the nitrosoaniline dephostatin, it can mimic phosphotyrosine substrate for Tyrosyl-DNA phosphodiesterase I (TdpI).

3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE 공급 업체

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