Anti-S.cerevisiae homolog of RAD24, Anti-hRad17

Anti-S.cerevisiae homolog of RAD24, Anti-hRad17 화학적 특성, 용도, 생산

• 용도

  Anti-RAD17 (N-terminal) antibody produced in rabbit has been used in immunoblotting and immunoprecipitation.

• 일반 설명

  Cell cycle checkpoint protein RAD17 is mapped to human chromosome 5q13.2 . It is also called s a replication factor C (RFC)-like DNA damage sensor protein. Eight alternative spliced transcript variants of the gene, which encode four distinct proteins, have been reported.

• Biochem/physiol Actions

  RAD17 has been reported in breast, non-small cell lung carcinoma and breast cancer. RAD17 is a critical event during checkpoint signaling in DNA-damaged cells. Treatment of human cells with genotoxic agents induced ATM/ATR dependent phosphorylation of RAD17 at Ser635 and Ser645 , suggesting that phosphorylation of RAD17 is a critical event during checkpoint signaling in DNA-damaged cells.

Anti-S.cerevisiae homolog of RAD24, Anti-hRad17 공급 업체

Global(2)Suppliers