스테포르핀

스테포르핀 화학적 특성, 용도, 생산

• 개요

  A simple aporphine alkaloid found in Stephania sasakii Hayata, the alkaloid has [α]_D - 90.6° (MeOH) and forms pale yellow needles when crystallized from Me2CO-Et20. The alkaloid occurs in the non-phenolic fraction of the alkaloidal extract from the plant and with AC20 in pyridine forms the O-acetate. The structure of the base has been determined by spectroscopic methods. The absolute configuration of the 6 -position has been established as R from the ORD determinations but as yet the steric configuration of the hydroxyl group remains to be clarified.

• 참고 문헌

  Kunimoto et al., Tetrahedron Lett., 3287 (1969)
  Kunimoto et al., J. Pharm. Soc., Japan, 92, 1496 (1972)