팔미토일펜타펩타이드-4

한글명:팔미토일펜타펩타이드-4

카스 번호214047-00-4

상품명:Palmitoyl Pentapeptide

CBNumberCB51214034

분자식C39H75N7O10

포뮬러 무게802.05

MOL 파일214047-00-4.mol

동의어(한글)

팔미토일펜타펩타이드-4

화학적 성질

끓는 점	1120.1±65.0 °C(Predicted)
밀도	1.147
저장 조건	2-8°C(protect from light)
산도 계수 (pKa)	2.98±0.10(Predicted)
물리적 상태	Solid
색상	White to off-white
시퀀스	pal-Lys-Thr-Thr-Lys-Ser-OH
InChIKey	WSGCRSMLXFHGRM-DEVHWETNSA-N
SMILES	C(O)(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H](CCCCN)NC(=O)CCCCCCCCCCCCCCC

팔미토일펜타펩타이드-4 화학적 특성, 용도, 생산

개요
Palmitoyl pentapeptide-4 (formerly called palmitoyl pentapeptide-3) was the fi rst big successful breakthrough peptide ingredient and probably the most commonly used peptide for aging skin. Also known as Matrixyl?, palmitoyl pentatpeptide-4 has been demonstrated to signifi cantly increase collagen synthesis, improving the appearance of wrinkles and sagging of the aging skin. Palmitoyl pentapeptide-4 is basically a sequential piece of a collagen molecule. It is theorized to work by “tricking” the skin into “believing” that too much collagen has been broken down, thereby curbing the production of collagenase, the enzyme that destroys collagen, and stimulating fi broblasts, the cells that produce collagen. The results of using palmitoyl pentapeptide-4 are remarkable, and the performance ingredient does not cause the irritation that can be caused by other antiaging ingredients such as retinol.
용도
palmitoyl pentapeptide-4 is a skin conditioner. Clinical studies by manufacturers credit it with an ability to promote collagen, elastin, and glycosaminoglycan synthesis. This would result in an ability to restore skin thickness, which diminishes with age, and to reduce the appearance of lines and wrinkles. Palmitoyl pentapeptide4 is a synthetic peptide with serine, threonine, and hexa decanoyl derivatives.
palmitoyl tetrapeptide-7 is formerly known as palmitoyl tetrapeptide3. This peptide appears to improve skin elasticity and firmness. It also hydrates, smoothes, and protects the skin. It can be both obtained from the plant and synthetically derived and is found in a variety of different skin care preparations including eye lotions, moisturizers, and night creams. Palmitoyl tetrapeptide3 appears to act as an anti-inflammatory. This is attributed to its ability to control the secretion of specific chemicals responsible for skin aging (i.e., cytokines and interleukin-6), and hence it may function in a manner similar to the anti-aging hormone, DHeA. Some studies indicate that palmitoyl tetrapeptide-7 may also act as a uV filter.
Mechanism of action
Palmitoyl Pentapeptide appears to work by increasing collagen production, stimulating collagen, elastin, and hyaluronic acid growth, increasing the skin's moisture content and retention, which helps reduce the appearance of fine lines and wrinkles on the skin's surface. Pentapeptide is equivalent to intimate integration with the skin, changing the skin ecology and cell repair, and playing the role of intracellular hormones and enzymes.

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