eritrityl tetranitrate

eritrityl tetranitrate 화학적 특성, 용도, 생산

• 화학적 성질

  Crystals. Soluble in alcohol, ether, and glycerol; insoluble in water.

• 용도

  Vasodilator (coronary). Cardilate (Glaxo Wellcome{) [Name previously used: Erythrol Tetranitrate.].

• 정의

  ChEBI: Erythritol in which each of the hydroxy groups has been converted to the corresponding nitrate ester. It is a vasodilator with properties similar to nitroglycerin. It is usually used diluted with lactose or other suitable inert excipients, in order to mini ise the risk of explosion; undiluted erythrityl tetranitrate can be exploded by percussion or excessive heat.

• 위험도

  Severe explosion risk when shocked or heated.

• Purification Methods

  Crystallise cordite from EtOH. It explodes on percussion at ~220-460o and is a vasodilator. [Beilstein 1 III 2358, 1 IV 2809.]

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