4'-클로로-3,5-디메톡시-4-(2-모르폴리노에톡시)벤조페논염산염

4'-클로로-3,5-디메톡시-4-(2-모르폴리노에톡시)벤조페논염산염 화학적 특성, 용도, 생산

• Originator

  Plausitin,Carlo Erba,Italy,1975

• Manufacturing Process

  Sodium methoxide (1.2 g) in dimethylformamide (150 ml) was stirred with 3,5-dimethoxy-4'-chloro-4-hydroxybenzophenone (6 g) in dimethylformamide (50 ml), for 2 hours at 120°C. The reaction mixture was then treated with β- morpholinoethyl chloride (3.4 g) and heated for 1 hour at 140C, then evaporated to dryness, and treated with water to give a solid material. The mixture was filtered, washed and crystallized from cyclohexane to give 3,5- dimethoxy-4'-chloro-4-(β-morpholinoethoxy)-benzophenone (6.5 g), MP 91°C to 92°C. The product was then reacted at about 0°C with gaseous hydrogen chloride in ether to give, after crystallization from isopropanol, the corresponding hydrochloride which had a MP of 187.9°C.

• Therapeutic Function

  Antitussive

4'-클로로-3,5-디메톡시-4-(2-모르폴리노에톡시)벤조페논염산염 준비 용품 및 원자재

4'-클로로-3,5-디메톡시-4-(2-모르폴리노에톡시)벤조페논염산염 공급 업체

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4'-클로로-3,5-디메톡시-4-(2-모르폴리노에톡시)벤조페논염산염 관련 검색