암페트아민

한글명:암페트아민

카스 번호300-62-9

상품명:D/L-AMPHETAMINE HYDROCHLORIDE

CBNumberCB4716187

분자식C9H13N

포뮬러 무게135.21

MOL 파일300-62-9.mol

동의어(한글)

암페트아민

암페타민

중추신경계에작용하는교감신경흥분성아민및그염류

화학적 성질

녹는점	146 °C
끓는 점	bp760 200-203°; bp13 82-85°
밀도	d425 0.913
증기 밀도	4.65
굴절률	1.5180 (estimate)
인화점	9℃
저장 조건	-20°C
용해도	클로로포름(약간 용해됨)
산도 계수 (pKa)	9.94±0.10(Predicted)
물리적 상태	액체 또는 오일
EPA	Amphetamine (300-62-9)

위험 및 안전 성명

위험품 표기

F,T

위험 카페고리 넘버

11-23/24/25-39/23/24/25

안전지침서

16-36/37-45-7

유엔번호(UN No.)

1851

WGK 독일

위험 등급

6.1(a)

포장분류

유해 물질 데이터

300-62-9(Hazardous Substances Data)

독성

LD50 in rats (mg/kg): 180 s.c. (Warren, Werner)

NFPA 704:

	1
3		0

그림문자(GHS)

암페트아민 화학적 특성, 용도, 생산

화학적 성질
Colorless, volatile liquid; characteristic strong odor; slight burning taste. Soluble in alcohol and ether; slightly soluble in water.
용도
Stimulant (central).
World Health Organization (WHO)
Amfetamine and its derivatives are potent central stimulants. Use of amfetamines has widely been discouraged due to abuse of their euphoric effect and their limited field of usefulness. Amfetamines have a place in the treatment of narcolepsy and in hyperkinetic syndrome in children. However, they are no longer recommended for use in obesity or depressive illness. Amfetamine is controlled under Schedule II of the 1971 Convention on Psychotropic Substances. (Reference: (UNCPS2) United Nations Convention on Psychotropic Substances (II), , , 1971)
일반 설명
Colored liquid with an amine odor. Used as a pharmaceutical, a central nervous system stimulant.
반응 프로필
Amines, such as D/L-AMPHETAMINE HYDROCHLORIDE, are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
위험도
Flammable, moderate fire risk. Basis of a group of hallucinogenic (habit-forming) drugs that affect the central nervous system. Sale and use restricted to physicians. Production limited by law.
건강위험
D/L-AMPHETAMINE HYDROCHLORIDE is classified as extremely hazardous. Probable lethal dose in humans is 5-50 mg/kg or 7 drops to 1 teaspoon for a 70 kg (150 lb.) person. Habit forming drug which affects the central nervous system. Excessive use may lead to tolerance and physical dependence. Death is possible.
화재위험
Dangerous when exposed to heat or flames. Upon decomposition, nitrogen oxides are emitted. Can react with oxidizing materials.
Safety Profile
A deadly human poison by an unspecified route. An experimental poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Experimental reproductive effects. Mutation data reported. A central nervous system stimulant. Overdoses cause hyperactivity, restlessness, insomnia, rapid pulse, rise in blood pressure, dilated pupils, dryness of the throat. Combustible when exposed to heat, flame, or oxidizers. When heated to decomposition it emits toxic fumes of NO,. To fight fire, use CO2, dry chemical, alcohol foam, water mist, fog. See other benzedrine entries.
잠재적 노출
Amphetamine is used as a pharmaceutical. It is a CNS stimulant.
환경귀착
Amphetamines are indirect acting sympathomimetics, producing their effects by inhibiting the transporters of dopamine, norepinephrine, and serotonin at the presynaptic nerve terminal. This increases the release of norepinephrine, dopamine, and serotonin and increased norepinephrine levels at central synapses, which further stimulates alpha and beta receptors. Some amphetamines also inhibit monoamine oxidase, preventing the breakdownof catecholamines. Thesemechanisms combine to produce the sympathomimetic and central nervous system (CNS) effects seen with amphetamine abuse.
운송 방법
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
비 호환성
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
폐기물 처리
It is inappropriate and possibly dangerous to the environment to dispose of expired or waste pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

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