(+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE
한글명:(+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE
카스 번호42542-10-9
상품명:(+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE
CBNumberCB4221584
분자식C11H15NO2
포뮬러 무게193.25
MOL 파일42542-10-9.mol
화학적 성질
| 끓는 점 | bp0.4 100-110° |
| 밀도 | 1.100±0.06 g/cm3(Predicted) |
| 인화점 | 9℃ |
| 저장 조건 | 2-8°C |
| 산도 계수 (pKa) | 10.32±0.10(Predicted) |
| InChIKey | SHXWCVYOXRDMCX-UHFFFAOYSA-N |
| EPA | 1,3-Benzodioxole-5-ethanamine, N,.alpha.-dimethyl- (42542-10-9) |
| 위험품 표기 | F,T |
| 위험 카페고리 넘버 | 11-23/24/25-39/23/24/25 |
| 안전지침서 | 7-16-36/37-45 |
| 유엔번호(UN No.) | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK 독일 | 1 |
| 유해 물질 데이터 | 42542-10-9(Hazardous Substances Data) |
| 독성 | A novel psychoactive drug chemically related to the hallucinogenic agent MDA, but reported to be non-hallucinogenic. Obtained by direct synthesis, at high doses it is reported to show a stimulant-like effect in animals. Its LD50 is 97 mg/kg, i. p., 49 mg/kg, i.p., 14 mg/kg, i.v., and 22 mg/kg, i.v. in mice, rats, dogs, and monkeys, respectively. At higher doses, MDMA has pressor effects and produces tachycardia, and causes damage to serotonin neurons in both rats and monkeys. The (S)- (1)-enantiomer is more active than the (R)-(?′)-enantiomer and, like amphetamine, the pharmacological effects may be due to a release of endogenous monoamine neurotransmitter, probably serotonin and/or norepinephrine. MDMA is also an inhibitor of monoamine uptake into brain synaptosomes. Symptoms include pronounced mydriasis, with nystagmus and jaw clenching, and nausea also is often reported. This substance produces a feeling of well-being and euphoria and is similar in some respects to MDA, in that it seems to enhance a sense of empathy and emotional openness in users. Toxic reactions would appear to occur as a result of the pressor action, and sympathomimetic effects of the drug. No appropriate therapeutic intervention has been reported. Peripheral adrenergic blocking agents, or chlorpromazine, have been used, however, to prevent death in dogs following a lethal i.v. dose of the chemically related agent MDA. |
