프로토스테파닌

프로토스테파닌 화학적 특성, 용도, 생산

• 개요

  A Stephania alkaloid, this base is found in S. japonica Miers. It forms colourless prisms from MeOH which contain solvent of crystallization, m.p. 75°C. The solvent may be removed under vacuum when the dry alkaloid has a higher melting point of 90-S°C. It is optically inactive and yields crystalline saits, e.g. the hydrochloride, m.p. 150°C (dec.); platinichloride, orange prisms, m.p. 223°C (dec.); methiodide, m.p. 220-loC and the methomethylsulphate, m.p. 235°C after sintering at 227°C. The structure has recently been confirmed by a synthesis which follows a route related to the biosynthetic pathway.

• 참고 문헌

  Kondo, Watanabe., J. Pharrn. Soc., Japan, 58,46 (1938)
  Kondo, Takeda., Chern. Abstr., 49, 1076 (1955)
  Synthesis: Battersby et al., Chern. Cornrnun., 20, 1214 (1968)

프로토스테파닌 준비 용품 및 원자재