루굴로바신A

루굴로바신A 화학적 특성, 용도, 생산

• 개요

  A non-crystallizable alkaloid, this base has been obtained from cultures of Penicillium concavorugulosum. It is slightly laevorotatory with [α]²²₄₃₆ - 3.0° (c 1.0, pyridine). The five-membered lactone ring is unsaturated and on catalytic hydrogenation the alkaloid forms the crystalline dihydro derivative, m.p. l49-l5l oC. One of the nitrogen atoms is present in the indole ring, the other being a methylamino group.

• 참고 문헌

  Abe et al., Agr. Bioi. Chern., (Tokyo), 33, 469 (1969)
  Abe et al., Nippon Nogeikagaku Kaishi, 43, 575 (1969)
  Yamatodani et al., Agr. Bioi. Chern., (Tokyo), 34,485 (1970)