AMYLOID BETA-PROTEIN (HUMAN, 1-40) TRIFLUOROACETATE

AMYLOID BETA-PROTEIN (HUMAN, 1-40) TRIFLUOROACETATE 화학적 특성, 용도, 생산

• 용도

  Amyloid β-protein is neurotrophic and neurotoxic in vivo and in vitro in human and rat neuronal cell cultures. β-Amyloid peptides (amino acids 1-42 and 1-43) are the major constituents of senile plaques and neurofibrillary tangles that occur in the hippoc

• 일반 설명

  Amyloid β Protein Fragment 1-40 (Aβ40) is derived from the amyloid-β protein (Aβ), which is mapped to human chromosome 21q21.3. Aβ40 is predominantly present in the vascular amyloid deposits. Aβ40 comprises of C-terminal membrane insertion domain. It shows structural transition from random coil to a α-helical structure in a water-micelle medium.

• Biochem/physiol Actions

  Amyloid β-protein is neurotrophic and neurotoxic in vivo and in vitro in human and rat neuronal cell cultures. β-Amyloid peptides (amino acids 1-42 and 1-43) are the major constituents of senile plaques and neurofibrillary tangles that occur in the hippocampus, neocortex, and amygdala of patients with Alzheimer′s disease.

AMYLOID BETA-PROTEIN (HUMAN, 1-40) TRIFLUOROACETATE 공급 업체

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