아세틸헥사펩타이드-24아마이드

아세틸헥사펩타이드-24아마이드 화학적 특성, 용도, 생산

• 용도

  Argireline is an anti-wrinkle peptide. Synthetically produced and considered to be highly effective, clinical studies indicate it can reduce the depth of existing wrinkles. May be incorporated into products marketed as having a topical-BoToX. or “wrinkle-erasing” effect.

• Clinical claims and research

  Argireline is a synthetic oligopeptide that emulates the sequence of SNAP-25, a type of SNARE. It has significant skin permeation, interferes with the SNARE ternary complex, and has demonstrated interference with catecholamine release from chromaffin cells. Topical use of 10% argireline resulted in a reduced depth and roughness of periorbital wrinkles in 10 healthy women. One study on 14 volunteers showed that 5% argireline reduced periorbital wrinkles by 32% in 28 days. Most recently, argireline’s efficacy has been measured in 60 Chinese women from a randomized control trial. Its total efficacy was 48.9% compared to 0% in the placebo group, and resulted in significantly decreased wrinkle roughness.

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