Pentosan may be useful in treating osteoarthritis in dogs, cats, and
horses. It has been used as an adjunctive treatment of feline interstitial
cystitis (feline idiopathic lower urinary tract disease—FLUTD).
Studies using pentosan for FLUTD have demonstrated that it is not
effective for short-term, acute lower urinary tract disease, but some
patients may benefit when it is used for chronic, persistent signs
associated with FLUTD.
