rifamide

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H319：눈에 심한 자극을 일으킴

• 예방조치문구

  P264：취급 후에는 손을 철저히 씻으시오.

  P264：취급 후에는 손을 철저히 씻으시오.

  P280：보호장갑/보호의/보안경/안면보호구를 착용하시오.

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

rifamide 화학적 특성, 용도, 생산

• 용도

  Antibacterial.

• Pharmaceutical Applications

  The diethyl amide of rifamycin B, formulated as the sodium salt for parenteral administration. It exhibits high activity against Gram-positive organisms and M. tuberculosis typical of the group. MICs for Gram-negative bacilli are of the order of 20–50 mg/L.
  It is absorbed orally and is rapidly eliminated through the bile, achieving concentrations sufficient to inhibit Gramnegative bacilli. In contrast to rifampicin, it can be administered as the sodium salt by intramuscular injection. A dose of 150 mg produces mean plasma levels of about 1 mg/L. The plasma halflife is about 2 h. The same dosage produces concentrations over 1 g/L in bile and c. 40 mg/L in the gallbladder wall.
  Toxicity and side effects are similar to those of other rifamycins. It has been used in staphylococcal infections and infections of the biliary tract. It is unsuitable for the treatment of tuberculosis because of insufficient distribution to the tissues.

rifamide 공급 업체

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