5,6-Dimethylpyridin-2-amine

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H302：삼키면 유해함

  H315：피부에 자극을 일으킴

  H319：눈에 심한 자극을 일으킴

  H335：호흡 자극성을 일으킬 수 있음

• 예방조치문구

  P261：분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

5,6-Dimethylpyridin-2-amine 화학적 특성, 용도, 생산

• 화학적 성질

  Light Yellow Low-Melting Solid

• Synthesis

  A mixture of 2-amino-5-bromo-6-methylpyridine (561 mg, 3.0 mmol), K2CO3 (1.24 g, 9.0 mmol) and Pd(dppf)Cl2·CH2Cl2 (245 mg, 0.30 mmol) was added to a solution of trimethylboroxine (377 mg, 3.0 mmol) in water (1 mL) and dioxane (10 mL). The mixture was heated at reflux for 3 h. After cooling to rt, the mixture was poured into water (50 mL). The mixture was extracted with diethyl ether (3*50ml), and the combined organic phases were dried (Na2SO4) and concentrated. Purification by chromatography (EtOAc/heptane) gave 5,6-Dimethylpyridin-2-amine as a black-brown solid. Yield: 67 %.
  

5,6-Dimethylpyridin-2-amine 공급 업체

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