(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy

(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy 화학적 특성, 용도, 생산

• 용도

  3β,7β-dihydroxy-5-cholestenoic acid may be used as an authentic diastereoisomer standard in mass spectrometry (MS) experiments.

• 일반 설명

  3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) is associated with plasma and is a C27 acid. 3β,7β-diHCA is synthesized from 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid (3βH,7O-CA) by the action of the enzyme hydroxysteroid 11-β dehydrogenase 1.

• Biochem/physiol Actions

  3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) levels are elevated in Niemann-Pick type C (NPC) disease and Niemann-Pick (NP) disease type B disorders. It elicits toxicity to oculomotor neurons.

(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy 공급 업체

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