2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Danger

• 유해·위험 문구

  H301：삼키면 유독함

  H318：눈에 심한 손상을 일으킴

  H413：장기적 영향에 의해 수생생물에 유해의 우려가 있음

• 예방조치문구

  P280：보호장갑/보호의/보안경/안면보호구를 착용하시오.

  P301+P310：삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole 화학적 특성, 용도, 생산

• 용도

  Neurodazine induces neurogenesis in mature skeletal muscle cells, via non-pluripotent C2C12 myoblasts.

• 일반 설명

  A cell-permeable trisubstituted imidazole compound that induces neurogenesis of non-pluripotent C2C12 myoblasts as well as cells derived from mature human skeletal muscle cultures (2 μM for 7-10 days). Shown to preferentially upregulate genes involved in neurogenesis, but not those pertaining to myogenesis, in C2C12 myoblasts.

• Biochem/physiol Actions

  Neurodazine is a promoter of neurogenesis. It induces a generation of new nerve cells from skeletal muscle fibers both immature, differentiated myotubes and mature skeletal muscle. Neurodazine promotes the expression of neuron-specific markers in treated C2C12 cells (neurogenesis). In addition, in conjunction with a microtubule-destabilizing agent, Neurodazine allows neurogenic conversion of both differentiated immature myotubes and mature skeletal muscle. Neurodazine is a potential alternative approach to using stem cells.

2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole 공급 업체

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